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Serratia marcescens Endocarditis

Sherif Elkattawy1, Mahsa Mohammadian1, Neil Williams2

  • 1Internal Medicine, Rutgers-New Jersey Medical School/Trinitas Regional Medical Center, Elizabeth, USA.

Cureus
|September 27, 2021
PubMed

Insights

Infective endocarditis (IE) caused by Serratia marcescens, a Gram-negative bacteria, is rare but serious. This report details two complex cases, highlighting the severity and management challenges of S. marcescens IE.

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Microbiology

Background:

  • Infective endocarditis (IE) is most commonly caused by Staphylococcus aureus and Streptococcus species.
  • Gram-negative bacterial IE, particularly by Serratia marcescens, is infrequent.
  • Intravenous drug use (IVDU) is a presumed risk factor for Serratia marcescens IE.

Observation:

  • Two cases of IE caused by Serratia marcescens are presented.
  • The first case involved IE of the tricuspid and aortic valves, necessitating surgery and complicated by an epidural abscess.
  • The second case presented with associated renal and splenic infarcts.

Findings:

  • Serratia marcescens IE can lead to severe and complicated clinical presentations.
  • These cases underscore the potential for significant morbidity associated with this rare form of IE.
  • The reported cases contribute to the limited literature on Serratia marcescens IE incidence and clinical course.

Implications:

  • Highlights the importance of considering Gram-negative pathogens in IE, especially in at-risk populations.
  • Emphasizes the need for prompt diagnosis and aggressive management of Serratia marcescens IE.
  • Provides valuable data for understanding the clinical spectrum and outcomes of Serratia marcescens IE.
Keywords:
infective endocarditisintravenous drug use (ivdu).renal infarctsserratia marcescenssplenic infarcts

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