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Idiopathic Aortitis With Retroperitoneal Fibrosis Course and Its Treatment.
Zaheer Faizi1, Ammar Humayun2, Marissa Matto3
1General Surgery, Crozer-Chester Medical Center, Upland, USA.
Cureus
|September 27, 2021
Summary
Idiopathic aortitis, an inflammation of the aorta, can cause serious complications. This case highlights successful treatment of idiopathic aortitis with corticosteroids, improving patient symptoms.
Area of Science:
- Vascular Inflammation
- Systemic Inflammatory Diseases
Background:
- Aortitis is inflammation of the aorta, with infectious or noninfectious causes.
- Noninfectious aortitis can stem from trauma or systemic inflammation, presenting diagnostic challenges.
- Idiopathic aortitis is diagnosed when the cause remains undetermined after thorough investigation.
Observation:
- A 67-year-old male presented with constitutional symptoms including malaise, abdominal pain, anorexia, and weight loss.
- Imaging revealed retroperitoneal fibrosis and signs of aortitis.
- The patient's symptoms persisted for several months prior to diagnosis.
Findings:
- Extensive workup led to a diagnosis of idiopathic aortitis.
- High-dose corticosteroid therapy was initiated for treatment.
- The patient experienced significant symptom improvement following treatment.
Implications:
- This case underscores the importance of considering idiopathic aortitis in patients with unexplained constitutional symptoms and aortic inflammation.
- Corticosteroids appear to be an effective treatment modality for idiopathic aortitis.
- Further research into the pathogenesis and optimal management of idiopathic aortitis is warranted.
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