Related Experiment Video
Updated: Oct 19, 2025

Inducing Post-Traumatic Epilepsy in a Mouse Model of Repetitive Diffuse Traumatic Brain Injury
Published on: February 10, 2020
Seizure after recovery from Covid-19
Sidhartha Chattopadhyay1, Sagar Basu1, Kamalesh Majumdar2
1Department of Neuro-Medicine, KPC Medical College and Hospital, Kolkata, West Bengal, India.
A young woman experienced a first-time seizure 14 days post-SARS-CoV-2 infection. Neurological imaging revealed focal cerebritis, which resolved with anti-epileptic treatment, highlighting a potential COVID-19 neurological complication.
Area of Science:
- Neurology
- Infectious Diseases
- Neuroscience
Background:
- Neurological complications of COVID-19 are diverse.
- Seizures represent a significant neurological manifestation.
- Understanding the link between SARS-CoV-2 and new-onset epilepsy is crucial.
Observation:
- A 27-year-old female with no prior seizure history presented with a generalized tonic-clonic seizure.
- The seizure occurred 14 days after a documented SARS-CoV-2 infection.
- The patient had a history of generalized anxiety disorder managed with SSRI.
Findings:
- Electroencephalogram (EEG) indicated post-ictal discharges.
- Magnetic Resonance Imaging (MRI) of the brain revealed focal cerebritis in both frontal lobes.
- The patient was treated with anti-epileptic drugs.
Implications:
- This case suggests a potential link between SARS-CoV-2 infection and new-onset seizures.
- Focal cerebritis may be a neurological consequence of COVID-19.
- Prompt anti-epileptic treatment led to complete resolution of EEG and MRI abnormalities, indicating potential for recovery.
More Related Videos
Related Concept Videos
Seizures: Classification
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Epilepsy and Seizures: Overview
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Antiepileptic Drugs: Potassium Channel Activators
Ezogabine has gained approval as an adjunctive treatment...
Electroconvulsive Therapy
Antiepileptic Drugs: Modulators of Neurotransmitter Release Mediated by SV2A Protein
SV2A is a transmembrane glycoprotein located predominantly in the brain, modulating the release of neurotransmitters for neuronal communication. Both levetiracetam and brivaracetam exhibit a high affinity for...
Antiepileptic Drugs: GABAergic Pathway Potentiators
The key GABA pathway potentiators used in epilepsy management are as follows.
Benzodiazepines are a well-known class of drugs used for...

