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[Non-pharmacological intervention in post-traumatic amnesia, a systematic review]
E Vilageliu-Jordà1,2,3, A Enseñat-Cantallops2,1,3, A García-Molina2,4,1,3
1Universitat Autònoma de Barcelona, Bellaterra, España.
Revista De Neurologia
|September 27, 2021
Summary
Non-pharmacological interventions effectively reduce cognitive and behavioral symptoms in survivors of traumatic brain injury (TBI) experiencing post-traumatic amnesia. This review highlights positive outcomes from various therapeutic approaches.
Area of Science:
- Neuroscience
- Rehabilitation Medicine
- Cognitive Psychology
Background:
- Survivors of traumatic brain injury (TBI) may experience post-traumatic amnesia, a state of confusion and cognitive-behavioral dysfunction.
- Understanding and managing post-traumatic amnesia is crucial for TBI recovery.
Purpose of the Study:
- To review and analyze studies on non-pharmacological interventions for post-traumatic amnesia symptoms.
- To assess the characteristics, methodological quality, and outcomes of these interventions.
Main Methods:
- A systematic literature search was conducted using PRISMA guidelines across PubMed and PsycInfo (2000-2020).
- Methodological quality was evaluated using the PEDro scale.
- Eight studies met inclusion criteria, including four randomized clinical trials.
Main Results:
- Interventions included activities of daily living retraining, reality orientation, the Perceive, Recall, Plan and Perform system, and music therapy.
- Seven out of eight reviewed studies reported positive or partially positive results.
- Non-pharmacological approaches demonstrated efficacy in addressing cognitive and behavioral deficits.
Conclusions:
- Evidence supports the positive impact of non-pharmacological interventions on post-traumatic amnesia symptoms.
- These interventions offer a viable strategy for managing cognitive-behavioral sequelae of TBI.
- Further research may refine these therapeutic approaches for optimal patient outcomes.

