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Institutional approaches to preventing questionable research practices.

Jesse D Troy1, Frank Rockhold1, Gregory P Samsa1

  • 1Department of Biostatistics and Bioinformatics, Duke University, Durham, North Carolina, USA.

Accountability in Research
|September 27, 2021
PubMed
Summary

Questionable research practices (QRP) are common, risking institutions and participants. New institutional strategies, especially for financial conflicts of interest, are needed to mitigate these research integrity issues.

Keywords:
Questionable research practicesconflict of interestintellectual property

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Area of Science:

  • Research Integrity
  • Scientific Misconduct
  • Research Ethics

Background:

  • Questionable research practices (QRP) are prevalent, indicating current mitigation strategies are insufficient.
  • QRP pose significant risks to research institutions and participants.
  • Existing approaches to managing QRP have proven inadequate.

Purpose of the Study:

  • To discuss the risks associated with QRP.
  • To propose institutional-level mitigation strategies for QRP.
  • To highlight the need for enhanced conflict of interest management.

Main Methods:

  • Editorial review of QRP risks and existing management strategies.
  • Case example: questionable treatment of subgroup analyses.
  • Proposal for expanding traditional conflict of interest management.

Main Results:

  • QRP are widespread and pose substantial risks.
  • Current methods for addressing QRP are insufficient.
  • Financial conflicts of interest exacerbate the need for institutional intervention.

Conclusions:

  • Institutional intervention is crucial for mitigating QRP.
  • Expanding conflict of interest management processes is necessary.
  • Addressing QRP is vital for maintaining research integrity and protecting stakeholders.