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[Mycoplasma meningoencephalitis and encephalomyelitis in children]
Zhurnal Nevropatologii I Psikhiatrii Imeni S.S. Korsakova (Moscow, Russia : 1952)
|January 1, 1978
Summary
Generalized mycoplasmic infections can cause severe central nervous system (CNS) damage, including meningoencephalitis, in infants. Morphological studies confirmed mycoplasma as the causative agent, highlighting diagnostic challenges due to varied neurological symptoms.
Area of Science:
- Neurology
- Infectious Diseases
- Pathology
Context:
- Generalized mycoplasmic infections in infants.
- Fatal cases of meningoencephalitis and encephalomyelitis.
- Clinico-morphological studies of the central nervous system (CNS).
Purpose:
- To investigate the clinico-morphological findings of generalized mycoplasmic infections in the CNS of deceased infants.
- To identify Mycoplasma as the causative agent of CNS lesions.
- To describe the clinical presentation and diagnostic difficulties associated with these infections.
Summary:
- Morphological studies of the CNS in 7 infants revealed structural changes and confirmed Mycoplasma as the infectious agent.
- Clinical diagnosis is challenging due to polymorphic neurological signs, including cortical and subcortical dysfunction, brainstem, and spinal cord pathology.
- Initial symptoms included convulsive syndrome (5 cases) or bulbar disorders (2 cases), suggesting potential intrauterine CNS lesions.
Impact:
- Provides crucial clinico-morphological data on infant mycoplasmic CNS infections.
- Highlights the diagnostic complexity and varied clinical manifestations.
- Suggests the possibility of intrauterine transmission and CNS involvement.