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Updated: Oct 19, 2025

FISH for Pre-implantation Genetic Diagnosis
Published on: February 23, 2011
[Epignathus, the importance of prenatal diagnosis and interdisciplinary work: A case report]
Camila Parellada1, Mónica N Pose2, Mariana Vázquez Durand2
1Sección Neonatología y Departamento de Pediatría, Hospital Universitario CEMIC, Ciudad Autónoma de Buenos Aires, Argentina. camilaparellada@gmail.com.
Abstract:
Thanks to technological advances, it has been possible to carry out the prenatal diagnosis of different life-threatening congenital malformations. Among these, oral teratoma, or epignathus, is a rare form of congenital teratoma within those located in the head and neck. They are generally benign and comprise 4 % of neonatal teratomas. From the development of the EXIT technique (ex utero intrapartum treatment), which has been implemented since the 90's to support fetal circulation until the newborn's airway is secured, it is possible to plan a multidisciplinary management strategy that enables the correct approach of these pathologies. We present a case of giant epignathus in a 35-week gestation female patient, whose airway was secured using the EXIT technique, and follow up.
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