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Updated: Jul 25, 2026

Assessment of Ovarian Cancer Spheroid Attachment and Invasion of Mesothelial Cells in Real Time
Published on: May 20, 2014
[Hypercalcemia in a pediatric patient with ovarian dysgerminoma: A case report]
Florencia Recanatini1, Ana L Feller2, María P Gonzalez2
1Servicio de Clínica pediátrica, Hospital de Pediatría SAMIC Prof. Dr. Juan P. Garrahan, Ciudad Autónoma de Buenos Aires, Argentina. florrecanatini@gmail.com.
Abstract:
Hypercalcemia associated with malignant tumors is a rare entity in pediatrics (0.5-1.3 % of pediatric cancers). It responds to different pathophysiological mechanisms and the typical symptoms shown are usually nonspecific, but potentially serious. We present a clinical case of a 12-year-old patient with a bilateral ovarian dysgerminoma who was diagnosed with severe hypercalcemia at the onset, which required hyperhydration associated with loop diuretics, bisphosphonates and, eventually, the tumor resection surgery that allowed the final resolution of the clinical picture. Despite being a rare hydroelectric disorder in pediatrics, given the potential severity of hypercalcemia, early detection and treatment are important in order to avoid potential short- and long-term complications.

