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Updated: Oct 18, 2025
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Determination of Biofilm Initiation on Virus-infected Cells by Bacteria and Fungi
Published on: July 6, 2016
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Biofilm Producing Enterococcus Isolates from Vaginal Microbiota
Mallika Sengupta1, Soma Sarkar2, Manideepa SenGupta3
1Department of Microbiology, All India Institute of Medical Sciences (AIIMS) Kalyani, Kalyani 741245, West Bengal, India.
Antibiotics (Basel, Switzerland)
|September 28, 2021
Summary
Enterococcus species are a common cause of vaginitis. Biofilm production in these isolates is a significant virulence factor, highlighting its role in infection.
Area of Science:
- Microbiology
- Infectious Diseases
- Clinical Science
Background:
- Enterococcus species are significant pathogens causing infections in both hospital and community settings.
- Vaginitis is a common condition where Enterococcus can be implicated.
Purpose of the Study:
- To investigate the characteristics of Enterococcus isolates from vaginitis cases.
- To determine antimicrobial susceptibility and biofilm production in these isolates.
Main Methods:
- Prospective study conducted over two years.
- Identification using Gram stain, biochemical tests, and VITEK 2 Compact.
- Antimicrobial susceptibility testing via disc diffusion and MIC determination.
- Biofilm detection assays performed on isolates.
Main Results:
- 39 Enterococcus isolates were identified from vaginitis cases (27 Enterococcus faecalis, 12 Enterococcus faecium).
- All isolates demonstrated high susceptibility to vancomycin, teicoplanin, and linezolid.
- Eight isolates (61.5%) exhibited biofilm production, with five strong and three moderate producers.
Conclusions:
- Biofilm production is a key virulence factor in Enterococcus isolates associated with vaginitis.
- Understanding these factors is crucial for managing Enterococcus-related vaginitis.
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