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Updated: Oct 18, 2025

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Published on: August 8, 2025
Check the Need-Prevalence and Outcome after Transvenous Cardiac Implantable Electric Device Extraction without
Giuseppe D'Angelo1, David Zweiker1,2,3, Nicolai Fierro1
1Department of Cardiac Electrophysiology and Arrhythmology, IRCCS San Raffaele Scientific Institute, San Raffaele Hospital, Vita-Salute University, 20132 Milan, Italy.
Background:
after transvenous lead extraction (TLE) of cardiac implantable electric devices (CIEDs), some patients may not benefit from device reimplantation. This study sought to analyse predictors and long-term outcome of patients after TLE with vs. without reimplantation in a high-volume centre.
Methods:
all patients undergoing TLE at our centre between January 2010 and November 2015 were included into this analysis.
Results:
a total of 223 patients (median age 70 years, 22.0% female) were included into the study. Cardiac resynchronization therapy-defibrillator (CRT-D) was the most common device (40.4%) followed by pacemaker (PM) (31.4%), implantable cardioverter-defibrillator (ICD) (26.9%), and cardiac resynchronization therapy-PM (CRT-P) (1.4%). TLE was performed due to infection (55.6%), malfunction (35.9%), system upgrade (6.7%) or other causes (1.8%). In 14.8%, no reimplantation was performed after TLE. At a median follow-up of 41 months, no preventable arrhythmia-related events were documented in the no-reimplantation group, but 11.8% received a new CIED after 17-84 months. While there was no difference in short-term survival, five-year survival was significantly lower in the no-reimplantation group (78.3% vs. 94.7%, p = 0.014).
Conclusions:
in patients undergoing TLE, a re-evaluation of the indication for reimplantation is safe and effective. Reimplantation was not related to preventable arrhythmia events, but all-cause survival was lower.
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