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Author Spotlight: Evaluating Therapeutic Strategies to Enhance Liver Regeneration
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New Therapies of Liver Diseases: Hepatic Encephalopathy

Chiara Mangini1, Sara Montagnese1

  • 1Department of Medicine, University of Padova, 35128 Padova, Italy.

Journal of Clinical Medicine
|September 28, 2021
PubMed

Insights

Hepatic encephalopathy (HE) significantly impacts patients

Area of Science:

  • Hepatology
  • Neurology
  • Gastroenterology

Background:

  • Hepatic encephalopathy (HE) is a frequent complication in advanced liver disease.
  • HE profoundly affects patients' social roles, driving ability, and self-sufficiency.
  • Recurrent and persistent HE presents ongoing management challenges and societal burden.

Purpose of the Study:

  • To provide a pragmatic overview of recent advancements in hepatic encephalopathy management.
  • To summarize newly available and emerging treatments for HE.

Main Methods:

  • This study is a narrative review.
  • Literature search and synthesis of current research on HE management strategies.

Main Results:

  • Recent years have seen increased focus on HE, with refined definitions.
  • Several new drugs and alternative management strategies for HE are now available or in development.

Conclusions:

  • Hepatic encephalopathy remains a significant clinical challenge.
  • Ongoing research and development offer promising new therapeutic avenues for HE.

Keywords:
ammoniacirrhosisportal-systemic shuntvigilance

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