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Updated: Oct 18, 2025

Analysis of Oxidative Stress in Zebrafish Embryos
Published on: July 7, 2014
Oxidative Stress and NADPH Oxidase: Connecting Electromagnetic Fields, Cation Channels and Biological Effects
Christos D Georgiou1, Lukas H Margaritis2
1Department of Biology, Section of Genetics, Cell & Developmental Biology, University of Patras, 10679 Patras, Greece.
Abstract:
Electromagnetic fields (EMFs) disrupt the electrochemical balance of biological membranes, thereby causing abnormal cation movement and deterioration of the function of membrane voltage-gated ion channels. These can trigger an increase of oxidative stress (OS) and the impairment of all cellular functions, including DNA damage and subsequent carcinogenesis. In this review we focus on the main mechanisms of OS generation by EMF-sensitized NADPH oxidase (NOX), the involved OS biochemistry, and the associated key biological effects.
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