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Updated: Oct 18, 2025

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Treatment Modalities of Recurrent Oral Mucosal Melanoma In Situ
Philipp Becker1,2, Andreas Pabst1,2, Monika Bjelopavlovic3
1Department of Oral and Maxillofacial Surgery, Federal Armed Forces Hospital, Rübenacherstr. 170, 56072 Koblenz, Germany.
Abstract:
Oral mucosal melanoma (OMM) represents an extremely rare entity that is associated with a poor prognosis due to late diagnosis and early metastasis. Here, extensive surgical therapy is the therapy of choice. In contrary, for OMM in situ, the respective therapeutical recommendations are lacking. In this case report, treatment modalities of an OMM in situ of the palate, including the maxillary alveolar process, are reported. The tumor relapsed twice despite adequate surgical therapy and reconstruction. Therefore, irradiation was performed as an adjuvant therapy. At a follow-up of two years, the patient was free from recurrences.
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