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Updated: Oct 18, 2025

Biofunctionalized Prussian Blue Nanoparticles for Multimodal Molecular Imaging Applications
Published on: April 28, 2015
Recent Advances in Gadolinium Based Contrast Agents for Bioimaging Applications
Atiya Fatima1, Md Wasi Ahmad1, Abdullah Khamis Ali Al Saidi2
1Department of Chemical Engineering, College of Engineering, Dhofar University, P.O. Box 2509, Salalah 211, Sultanate of Oman.
Abstract:
Gadolinium (Gd) based contrast agents (CAs) (Gd-CAs) represent one of the most advanced developments in the application of Gd for magnetic resonance imaging (MRI). Current challenges with existing CAs generated an urgent requirement to develop multimodal CAs with good biocompatibility, low toxicity, and prolonged circulation time. This review discussed the Gd-CAs used in bioimaging applications, addressing their advantages and limitations. Future research is required to establish the safety, efficacy and theragnostic capabilities of Gd-CAs. Nevertheless, these Gd-CAs offer extraordinary potential as imaging CAs and promise to benefit bioimaging applications significantly.
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