Current directions in tau research: Highlights from Tau 2020

Area of Science:

• Neuroscience
• Biochemistry
• Pharmacology

Background:

• Tau deposition is strongly linked to neuronal loss, neurodegeneration, and cognitive decline.
• Tau and its related mechanisms are increasingly recognized as critical therapeutic targets.

Purpose of the Study:

• To convene global tau experts to discuss advances in tau research.
• To foster partnerships and support new drug discovery programs for tauopathies.
• To accelerate the pace of tau research through shared tools and insights.

Main Methods:

• A global conference (Tau2020) was held in February 2020.
• Presentations and discussions involved experts from academia, industry, government, and philanthropy.
• Focus on recent advances, current directions, and research-advancing tools in tau research.

Main Results:

• Facilitated global partnerships among diverse stakeholders in tau research.
• Provided support for new drug discovery programs, research, and emerging scientists.
• Accelerated research progress through the sharing of critical tools and insights.

Conclusions:

• The conference successfully moved tau research forward.
• Collaborative efforts and shared resources are key to advancing tau-targeted therapies.
• Continued focus on tau mechanisms is essential for combating neurodegenerative diseases.