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Tools for standardized data collection: Speech, Language, and Hearing measurement protocols in the PhenX Toolkit
Cynthia C Morton1, Mary L Marazita2, Beate Peter3
1Brigham and Women's Hospital, Harvard Medical School, Broad Institute of MIT and Harvard, University of Manchester, Manchester, UK.
Annals of Human Genetics
|September 28, 2021
Summary
The PhenX Toolkit updated its Speech, Language, and Hearing protocols. These enhancements improve data consistency for biomedical research, aiding cross-study analyses of communication and hearing disorders.
Area of Science:
- Biomedical Research
- Genetics
- Otolaryngology
- Audiology
- Speech-Language Pathology
Background:
- The PhenX Toolkit provides standardized measurement protocols for biomedical research.
- Ensuring data consistency across studies is crucial for accurate analysis and integration.
Purpose of the Study:
- To update the PhenX Toolkit's Speech and Hearing domain protocols.
- To enhance the precision and consistency of speech, language, and hearing disorder phenotypes.
- To reflect the latest scientific advancements and technological applications.
Main Methods:
- An expert review panel (ERP) convened in August 2018.
- The ERP reviewed and updated 28 measurement protocols.
- Additional experts in voice, vertigo, and stuttering provided input.
Main Results:
- Six new protocols were added: two for voice, three for hearing, and two for speech.
- Five existing protocols were updated.
- One protocol was retired.
- The domain name was updated to "Speech, Language, and Hearing" to include language protocols.
Conclusions:
- Updated protocols facilitate the assessment of speech, language, and hearing in clinical and population research.
- Standardized common data elements promote cross-study data integration.
- Increased statistical power is achievable through combined study data.
