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Assessment of Cardiac Morphological and Functional Changes in Mouse Model of Transverse Aortic Constriction by Echocardiographic Imaging
Published on: June 21, 2016
Advanced imaging tools for evaluating cardiac morphological and functional impairment in hypertensive disease
Maria Lembo1, Maria Virginia Manzi, Costantino Mancusi
1Department of Advanced Biomedical Sciences, Federico II University of Naples, Naples, Italy.
Insights
Advanced imaging techniques help detect cardiovascular injury in arterial hypertension, guiding better treatment and preventing disease progression. A multi-imaging approach offers a comprehensive view of hypertension-induced heart damage.
Area of Science:
- Cardiology
- Medical Imaging
Background:
- Arterial hypertension causes systemic cardiovascular damage, affecting heart structure and function.
- Cardiovascular injury in hypertension ranges from subclinical changes to overt organ damage and complications.
Purpose of the Study:
- To review the role of advanced imaging techniques in identifying and characterizing cardiovascular injury in arterial hypertension.
- To emphasize the utility of a multi-imaging approach for a comprehensive assessment of hypertensive cardiovascular damage.
Main Methods:
- Review of advanced imaging modalities including speckle tracking echocardiography, 3D echocardiography, cardiac MRI, CT, and PET-CT.
- Focus on how these techniques identify morphological and functional alterations in hypertensive cardiovascular injury.
Main Results:
- Advanced imaging can detect cardiovascular injury at various stages of arterial hypertension.
- These techniques provide crucial information for guiding timely management and therapy.
- Multi-imaging approaches offer a holistic view of hypertension-related cardiovascular damage.
Conclusions:
- Advanced imaging is vital for diagnosing and managing hypertensive cardiovascular injury.
- A multi-modal imaging strategy enhances diagnostic accuracy and aids in preventing disease progression.
- Comprehensive cardiovascular assessment through advanced imaging improves patient outcomes in arterial hypertension.
Abstract:
Arterial hypertension represents a systemic burden, and it is responsible of various morphological, functional and tissue modifications affecting the heart and the cardiovascular system. Advanced imaging techniques, such as speckle tracking and three-dimensional echocardiography, cardiac magnetic resonance, computed tomography and PET-computed tomography, are able to identify cardiovascular injury at different stages of arterial hypertension, from subclinical alterations and overt organ damage to possible complications related to pressure overload, thus giving a precious contribution for guiding timely and appropriate management and therapy, in order to improve diagnostic accuracy and prevent disease progression. The present review focuses on the peculiarity of different advanced imaging tools to provide information about different and multiple morphological and functional aspects involved in hypertensive cardiovascular injury. This evaluation emphasizes the usefulness of the emerging multiimaging approach for a comprehensive overview of arterial hypertension induced cardiovascular damage.
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