Related Experiment Video
Updated: Oct 18, 2025
Isolation of Proximal Fluids to Investigate the Tumor Microenvironment of Pancreatic Adenocarcinoma
Published on: November 5, 2020
Biomarkers for prognosis in pancreatic neuroendocrine tumors
Mojun Zhu1, Karl R Sorenson1, Rebecca Liu2
1Department of Oncology, Mayo Clinic, Rochester, Minnesota, USA.
Abstract:
Pancreatic neuroendocrine tumors (PNETs) encompass a diverse group of malignancies marked by histological heterogeneity and highly variable clinical outcomes. We performed a systematic review on potential prognostic biomarkers in PNETs by searching the PubMed database. A total of 472 manuscripts were reviewed in detail, of which 52 multivariate studies met the inclusion criteria proposed by the Reporting Recommendations for Tumor Marker Prognostic Studies. These altogether analyzed 53 unique targets, and 36 of them were statistically associated with survival.
