Two new sesquiterpenes from Xylopia vielana
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Updated: Oct 18, 2025

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
Ling Chen1, Ping Yang1, Mi Zhang1
1Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, Yunnan, P. R. China.
Abstract:
Two new sesquiterpenes (1-2) and six known analogues (3-8) were isolated from the branches and leaves of Xylopia vielana Pierre. The structures of the new compounds were identified by analyzing 1 D and 2 D NMR data and HRESIMS data, combined with induced and calculated circular dichroism experiments. In addition, compounds 1-4, 7 and 8 showed notable nitric oxide (NO) inhibitory effects (IC50 < 10 μM) on the model of the lipopolysaccharide (LPS)-activated RAW 264.7 macrophages.

