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Temporal Quantification of MAPK Induced Expression in Single Yeast Cells
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Publisher Correction: Measurement of histone replacement dynamics with genetically encoded exchange timers in yeast

Gilad Yaakov1, Felix Jonas2, Naama Barkai3

  • 1Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel. gilad.yaakov@weizmann.ac.il.

Nature Biotechnology
|September 29, 2021
PubMed
Abstract

No abstract available in PubMed .

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In 1928, a German botanist Emil Heitz observed the moss nuclei with a DNA binding dye. He observed that while some chromatin regions decondense and spread out in the interphase nucleus, others do not. He termed them euchromatin and heterochromatin, respectively. He proposed that the heterochromatin regions reflect a functionally inactive state of the genome. It was later confirmed that heterochromatin is transcriptionally repressed, and euchromatin is transcriptionally active chromatin.