Understanding multiseptated gallbladder: A systematic analysis with a case report

Area of Science:

• Gastroenterology
• Pediatric Surgery
• Medical Imaging

Background:

• Multiseptated gallbladder (MSG), also known as honeycomb gallbladder, is a rare congenital anomaly.
• Approximately 150 cases have been documented globally since its first description in 1952.
• MSG can manifest with diverse symptoms or be asymptomatic, with varied reported management strategies.

Purpose of the Study:

• To enhance understanding of multiseptated gallbladder (MSG).
• To review and analyze cases of MSG, including a pediatric patient.
• To evaluate current management approaches and outcomes for MSG.

Main Methods:

• Literature review and analysis of 97 reported cases of MSG.
• Inclusion of a case study of a 4-year-old girl with MSG.
• Analysis of diagnostic methods and treatment outcomes.

Main Results:

• The median age of presentation for MSG is 27 years, affecting all age groups and genders equally.
• Abdominal pain is the most common symptom, though asymptomatic cases occur.
• Cholecystectomy resolved symptoms in 13 of 40 patients, while medical treatment showed limited success in 4 of 8 patients.

Conclusions:

• Congenital MSG is likely caused by an in-pouching of the gallbladder wall forming septa.
• Ultrasound is an effective diagnostic tool for MSG.
• Cholecystectomy provides symptom resolution in some patients, but further research is needed on medical treatment efficacy.