Using EuGeneCiD and EuGeneCiM computational tools for synthetic biology
Related Experiment Video
Updated: Oct 18, 2025
Mapping Bacterial Functional Networks and Pathways in Escherichia Coli using Synthetic Genetic Arrays
Published on: November 12, 2012
Wheaton L Schroeder1,2, Anna S Baber2,3, Rajib Saha1,2
1Department of Chemical and Biomolecular Engineering, University of Nebraska - Lincoln, Lincoln, NE 68588, USA.
Abstract:
Synthetic biology often relies on the design of genetic circuits, utilizing "bioparts" (modular DNA pieces) to accomplish desired responses to external stimuli. While such designs are usually intuited, detailed here is a computational approach to synthetic biology design and modeling using optimization-based tools named Eukaryotic Genetic Circuit Design and Modeling. These allow for designing and subsequent screening of genetic circuits to increase the chances of in vivo success and contribute to the development of an application development pipeline. For complete details on the use and execution of this protocol, please refer to Schroeder, Baber, and Saha (2021).
