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Updated: Oct 18, 2025

Bile Duct Ligation in Mice: Induction of Inflammatory Liver Injury and Fibrosis by Obstructive Cholestasis
Published on: February 10, 2015
Canine intrahepatic biliary disease
1Department of Specialty Medicine, Midwestern University, College of Veterinary Medicine, 19555 N 59th Avenue, Glendale, AZ, 85308, USA.
Abstract:
The intrahepatic biliary tract is comprised of a complex network of conduits that are essential in the transportation and formation of bile with components needed for fat digestion and absorption as well as the elimination of catabolised compounds. Derangements in this system can have dangerous sequela that affects morbidity and mortality. This review aimed to summarise clinically relevant updates on intrahepatic biliary disorders in dogs including human corollaries.
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