Dissected aorta segmentation using convolutional neural networks

Tianling Lyu1, Guanyu Yang1, Xingran Zhao1

  • 1Laboratory of Imaging Science and Technology, Southeast University, Nanjing, China.

Insights

This study introduces a deep learning algorithm for segmenting dissected aortas in CT scans. The method accurately captures aortic structures, improving treatment planning for this critical cardiovascular condition.

Area of Science:

  • Medical Imaging
  • Cardiovascular Pathology
  • Artificial Intelligence in Medicine

Background:

  • Aortic dissection is a life-threatening condition characterized by a tear in the aorta's intimal layer.
  • Accurate 3-D morphological understanding of the dissected aorta is crucial for effective treatment planning.
  • Current segmentation methods require improvement for precise aortic dissection analysis.

Purpose of the Study:

  • To develop a deep-learning-based algorithm for automatic segmentation of dissected aortas in computed tomography angiography (CTA) images.
  • To enhance the accuracy and robustness of aortic dissection segmentation.
  • To provide a tool for better understanding the 3-D morphology of dissected aortas.

Main Methods:

  • A two-step deep learning approach utilizing 3-D and 2-D convolutional neural networks (CNNs).
  • Initial 3-D CNN divides the aorta into anatomical portions, followed by 2-D CNNs (PSPnet-based) for detailed segmentation.
  • Integration of an edge extraction branch to improve intimal flap segmentation accuracy.

Main Results:

  • The proposed algorithm achieved an average Dice index exceeding 92%, demonstrating high segmentation performance.
  • The combined 3-D and 2-D model approach outperformed 3-D or 2-D only models in accuracy and robustness.
  • The edge extraction branch significantly improved the Dice index near aortic boundaries from 73.41% to 81.39%.

Conclusions:

  • The developed deep learning algorithm effectively segments dissected aortas, accurately capturing complex structures.
  • The method demonstrates high performance in identifying the intimal flaps while minimizing false positives.
  • This tool aids in the precise morphological assessment of dissected aortas, supporting clinical decision-making.
Abstract

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