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Transcranial Direct Current Stimulation tDCS for Memory Enhancement
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Cognitive Stimulation for Persons with Dementia: a Systematic Review and Meta-Analysis.

Y L Wong1, C P W Cheng1, C S M Wong1

  • 1Department of Psychiatry, Queen Mary Hospital, Hong Kong.

East Asian Archives of Psychiatry : Official Journal of the Hong Kong College of Psychiatrists = Dong Ya Jing Shen Ke Xue Zhi : Xianggang Jing Shen Ke Yi Xue Yuan Qi Kan
|September 30, 2021
PubMed
Summary
This summary is machine-generated.

Cognitive stimulation (CS) significantly improves cognition in individuals with dementia. However, its effects on depressive symptoms and quality of life require further investigation.

Keywords:
CognitionDementiaMeta-analysisSystematic review

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Area of Science:

  • Neurology
  • Gerontology
  • Psychiatry

Background:

  • Dementia significantly impacts cognitive function, mood, and quality of life.
  • Cognitive stimulation (CS) is a non-pharmacological intervention explored for dementia management.
  • Evidence on the comprehensive effects of CS requires systematic evaluation.

Purpose of the Study:

  • To conduct a systematic review and meta-analysis on the effects of cognitive stimulation (CS) in persons with dementia.
  • To evaluate the impact of CS on cognition, depressive symptoms, and quality of life.
  • To identify factors influencing the treatment efficacy of CS.

Main Methods:

  • Systematic literature search across major databases (MEDLINE, EMBASE, PsycINFO, CINAHL Plus, Cochrane Library) up to March 2019.
  • Inclusion of 20 randomized controlled trials (RCTs) involving 1251 participants with mild to moderate dementia.
  • Meta-analysis of outcomes including cognitive function, depressive symptoms, and quality of life.

Main Results:

  • Cognitive stimulation demonstrated a significant small-to-moderate positive effect on cognitive function (Hedges's g = 0.313, p < 0.001).
  • Low to moderate heterogeneity was observed among the included CS studies (I² = 37.877%).
  • Inconclusive results were obtained regarding the effects of CS on depressive symptoms and quality of life.

Conclusions:

  • Cognitive stimulation is effective in enhancing cognitive function in people with dementia.
  • The impact of CS on depressive symptoms and quality of life remains uncertain.
  • Further high-quality research with robust methodologies is needed to establish the efficacy of CS for all assessed outcomes.