Machine Learning as a Tool in Investigating the Possible Role of Microbiome in Development and Treatment of Cancer

Sreehita Hajeebu1, Ngonack J Ngembus1, Pushyami Satya Bandi1

  • 1Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.

Cureus
|September 30, 2021
PubMed

Insights

Machine learning (ML) and artificial intelligence (AI) can analyze the microbiome

Area of Science:

  • Oncology and Bioinformatics
  • Microbiome research
  • Computational biology

Background:

  • Cancer is a leading global cause of death, necessitating novel therapeutic strategies.
  • The human microbiome's composition is increasingly recognized for its influence on cancer development and treatment.
  • Interactions between microbiota genetics and oncogenes present a new frontier in cancer research.

Purpose of the Study:

  • To explore the application of machine learning (ML), a form of artificial intelligence (AI), in understanding the microbiome's role in cancer.
  • To investigate how ML can aid in the detection and treatment of cancer through microbiome analysis.

Main Methods:

  • Review of current research on the microbiome and cancer.
  • Exploration of machine learning (ML) techniques applicable to complex biological data.
  • Discussion of the computational power required for microbiome-gene analysis in oncology.

Main Results:

  • Machine learning (ML) offers a powerful approach to analyze complex microbiome data in cancer research.
  • AI-driven analysis can potentially identify links between microbial composition and anti-tumor drug efficacy.
  • Investigating genetic correlations between microbiota and oncogenes is facilitated by ML.

Conclusions:

  • Machine learning (ML) is a promising tool for uncovering the microbiome's role in cancer detection and treatment.
  • AI can help decipher the intricate relationship between the microbiome and cancer therapeutics.
  • Further research utilizing ML is crucial for advancing microbiome-based cancer therapies.