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Updated: Oct 18, 2025

Efficient Synthesis of Polyfunctionalized Benzenes in Water via Persulfate-promoted Benzannulation of α,β-Unsaturated Compounds and Alkynes
Published on: December 16, 2019
TFBen (Benzene-1,3,5-triyl triformate): A Powerful and Versatile CO Surrogate
Hefei Yang1, Jiajun Zhang1, Zhengkai Chen1
1Department of Chemistry, Key Laboratory of Surface & Interface Science of Polymer Materials of Zhejiang Province, Zhejiang Sci-Tech University, Hangzhou, 310018, People's Republic of China.
Abstract:
Carbonylative reactions by the using of CO surrogates constitute a facile avenue for the assembly of valuable carbonyl-containing compounds due to the colorless, toxic, flammable, and not easy-handing character of carbon monoxide gas. Recent advances in the carbonylative transformations with TFBen (benzene-1,3,5-triyl triformate) as a safe and convenient CO precursor are systematically summarized and discussed, which can be divided into three parts based on the patterns of the obtained products. This Review focuses on the discussion of the application of TFBen in carbonylative synthesis of various carbonyl-containing compounds.
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