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Updated: Oct 18, 2025

Development of a More Sensitive and Specific Chromogenic Agar Medium for the Detection of Vibrio parahaemolyticus and Other Vibrio Species
Published on: November 8, 2016
Prevalence of Antimicrobial Resistant of Vibrio parahaemolyticus Isolated from Diarrheal Patients - Six PLADs, China,
Haihong Han1, Sara M Pires2, Johanne Ellis-Iversen3
1National Health Commission Key Laboratory of Food Safety Risk Assessment, Chinese Academy of Medical Science Research Unit (No.2019RU014), China National Center for Food Safety Risk Assessment, Beijing, China.
What Is Already Known On This Topic?:
Vibrio parahaemolyticus (V. parahaemolyticus) is frequently resistant to common antimicrobials such as ampicillin and generally highly susceptible to most clinically used antimicrobials.
What Is Added By This Report?:
V. parahaemolyticus were highly resistant to cefazolin and ampicillin: 94.4% and 37.0%, respectively. However, it was below 3% resistance to all 10 other antimicrobials including clinically relevant agents and even imipenem. The overall levels of antimicrobial resistance and multidrug resistance were 95.1% and 3.3%, respectively. The distribution of antimicrobial resistance and the multidrug resistance had regional, temporal, sexual, and isolated source strain variation.
What Are The Implications For Public Health Practice?:
This study provides data on drug resistance of V. parahaemolyticus in Chinese clinical settings, which will help develop a public health strategy.
Insights
Vibrio parahaemolyticus exhibits high resistance to cefazolin and ampicillin but remains susceptible to most other antibiotics. This study highlights significant variations in antimicrobial resistance patterns.
Area of Science:
- Microbiology
- Antimicrobial Resistance
- Public Health
Background:
- Vibrio parahaemolyticus (V. parahaemolyticus) often shows resistance to ampicillin and susceptibility to other antimicrobials.
- Understanding antimicrobial resistance patterns is crucial for effective treatment and public health strategies.
Purpose of the Study:
- To investigate the antimicrobial resistance profiles of V. parahaemolyticus in Chinese clinical settings.
- To identify variations in resistance patterns based on regional, temporal, sexual, and source factors.
Main Methods:
- Antimicrobial susceptibility testing was performed on V. parahaemolyticus isolates.
- Resistance rates to various antibiotics, including cefazolin, ampicillin, and imipenem, were determined.
- Multidrug resistance was assessed.
Main Results:
- High resistance rates were observed for cefazolin (94.4%) and ampicillin (37.0%).
- Resistance to 10 other antimicrobials, including imipenem, was below 3%.
- Overall antimicrobial resistance was 95.1%, with 3.3% multidrug resistance, showing significant variations.
Conclusions:
- V. parahaemolyticus in China displays significant resistance to specific antibiotics like cefazolin and ampicillin.
- The study provides essential data for developing targeted public health interventions and antimicrobial stewardship programs.
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