Outbreaks of Acute Respiratory Disease Associated with Human Adenovirus Infection in Closed Camps, China, December

Juan Du1, Xiaodong Zhao2, Fang Tang3

  • 1Department of Laboratorial Science and Technology, School of Public Health, Peking University, Beijing, China.

China CDC Weekly
|October 1, 2021
PubMed
Abstract

Insights

Human adenovirus (HAdV) causes acute respiratory disease (ARD) outbreaks in military settings. This study identified specific HAdV genotypes responsible for outbreaks in Chinese military camps, highlighting the need for targeted vaccines and quarantine measures.

Area of Science:

  • Public Health
  • Infectious Diseases
  • Epidemiology

Background:

  • Human adenovirus (HAdV) is a known cause of acute respiratory disease (ARD) outbreaks.
  • Military camps are recognized as high-risk environments for the spread of infectious diseases like ARD.

Purpose of the Study:

  • To identify the specific human adenovirus genotypes responsible for ARD outbreaks in Chinese military camps.
  • To determine the epidemiological characteristics and attack rates associated with these HAdV outbreaks.

Main Methods:

  • Retrospective analysis of ARD outbreak data from military camps in China between 2011 and 2014.
  • Identification of causative HAdV genotypes through laboratory testing (details not specified in abstract).

Main Results:

  • Human adenovirus types B7, B14, and B55 were identified as the primary causes of ARD outbreaks.
  • HAdV-B7, HAdV-B14, and HAdV-B55 were linked to 3, 2, and 4 outbreaks, respectively.
  • The overall attack rate for these HAdV outbreaks was 28.0%.

Conclusions:

  • Specific HAdV genotypes (B7, B14, B55) are significant contributors to ARD outbreaks in military populations.
  • Vaccine development and administration should be prioritized for military personnel.
  • Implementing quarantine for new recruits and identifying prevalent HAdV genotypes are crucial public health strategies.

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