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Red Blood Cell Distribution Width: Another Prognostic Factor for COVID-19?

Maria Lagadinou¹, Despoina Gkentzi², Markos N Marangos¹

¹Department of Internal Medicine, University Hospital of Patras, Greece.

Clinical Hematology International

|October 1, 2021

Summary

High red blood cell distribution width (RDW) indicates a higher risk of severe outcomes in COVID-19 patients. This simple blood test can help predict hospitalization and mortality, aiding early medical intervention for coronavirus disease 2019.

Keywords:

COVID-19 prognostic factor red blood cell distribution width

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Area of Science:

Medicine
Hematology
Infectious Diseases

Background:

Coronavirus disease 2019 (COVID-19) presents a significant global health challenge with high rates of severe illness and death.
Early identification of high-risk patients is crucial for timely and effective treatment strategies.
Elevated red blood cell distribution width (RDW) is a known predictor of mortality in various critical conditions.

Purpose of the Study:

To investigate if red blood cell distribution width (RDW) levels serve as an independent prognostic marker for COVID-19 severity.
To assess the correlation between RDW and hospitalization rates and disease outcomes in COVID-19 patients.

Main Methods:

Retrospective analysis of COVID-19 confirmed cases admitted to Patras University Hospital, Greece.
Measurement and evaluation of red blood cell distribution width (RDW) values upon admission.
Statistical analysis to determine the prognostic value of RDW for hospitalization and patient outcomes.

Main Results:

Preliminary findings suggest a potential association between higher RDW levels and adverse outcomes in COVID-19 patients.
Further analysis is required to establish RDW as an independent predictor.

Conclusions:

Red blood cell distribution width (RDW) may offer valuable prognostic information for COVID-19 patients.
This hematological parameter could potentially guide clinical decision-making for managing severe coronavirus disease 2019.