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Pulsatile Hemodynamics and Coronary Artery Disease

Hack-Lyoung Kim1, Thomas Weber2

  • 1Division of Cardiology, Department of Internal Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul National University College of Medicine, Seoul, Korea.

Korean Circulation Journal
|October 1, 2021
PubMed

Insights

Coronary artery disease (CAD) is a global health burden. This review explores how arterial pulsatile hemodynamics, like pulse wave velocity, can help predict cardiovascular events in CAD patients.

Area of Science:

  • Cardiovascular Medicine
  • Hemodynamics
  • Biomedical Engineering

Background:

  • Coronary artery disease (CAD) is a leading global cause of mortality.
  • Early detection and risk-stratified therapy are crucial for managing CAD.
  • Arterial pulsatile hemodynamics are gaining attention in cardiovascular research.

Purpose of the Study:

  • To review the pathophysiology linking arterial pulsatile hemodynamics and CAD.
  • To assess the utility of hemodynamic measurements in predicting cardiovascular events in CAD patients.
  • To discuss clinical and therapeutic implications.

Main Methods:

  • Review of existing literature on arterial pulsatile hemodynamics and CAD.
  • Analysis of commonly used hemodynamic measurements (e.g., pulse pressure, pulse wave velocity, augmentation index).
  • Examination of studies correlating hemodynamic parameters with cardiovascular event prediction.

Main Results:

  • Arterial pulsatile hemodynamics are associated with the pathophysiology of CAD.
  • Measurements like pulse wave velocity and augmentation index show potential in predicting future cardiovascular events.
  • Hemodynamic assessment offers valuable insights for risk stratification.

Conclusions:

  • Understanding the link between pulsatile hemodynamics and CAD is vital for risk assessment.
  • Hemodynamic parameters serve as useful non-invasive markers for predicting cardiovascular outcomes in CAD.
  • Individualized therapy can be enhanced by incorporating hemodynamic data.

Keywords:
Arterial stiffnessCoronary artery diseasePulsatile hemodynamicsPulse wave velocityWave reflections

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