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A case report about eosinophilic enteritis presenting as abdominal pain
Hairong Zhang1, Cuimei Ma1, Yuan Xue1
1Department of Gastroenterology, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, Shandong, P.R. China.
Medicine
|October 1, 2021
Summary
Eosinophilic enteritis (EE) is an immune-mediated disease. Steroid therapy effectively managed symptoms in a patient with EE, highlighting the importance of monitoring eosinophil counts and considering biopsies.
Area of Science:
- Gastroenterology
- Immunology
- Pathology
Background:
- Eosinophilic enteritis (EE) is an immune-mediated, antigen-driven condition.
- It is characterized by significant eosinophilic infiltration in the intestinal mucosa.
- EE can lead to clinical symptoms and organ dysfunction.
Observation:
- A 29-year-old male presented with abdominal pain and urge to defecate.
- Enteroscopy revealed acute and chronic inflammation with substantial eosinophilic infiltration (>20/HPF).
Findings:
- The patient received intravenous dexamethasone, followed by oral prednisolone.
- Symptomatic relief was achieved within 5 days of treatment.
- Post-treatment, eosinophil counts normalized.
Implications:
- EE management requires monitoring dynamic eosinophil counts.
- A history of allergies is not always present in EE patients.
- Multisite biopsies are recommended for suspected EE, which appears responsive to steroid therapy.
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