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Follow-up after acute thrombotic events following COVID-19 infection

Christopher M Faries1, Ajit Rao1, Nicole Ilonzo1

  • 1Department of Surgery, Division of Vascular Surgery, New York, NY.

Journal of Vascular Surgery
|October 1, 2021
PubMed

Insights

COVID-19 infection causes blood clots, leading to high mortality and complication rates in patients experiencing arterial thrombotic events. Follow-up revealed poor outcomes and low patency rates for treated patients.

Area of Science:

  • Vascular Surgery
  • Infectious Diseases
  • Cardiology

Background:

  • COVID-19 infection is associated with a hypercoagulable state.
  • Thrombotic events are a significant complication in patients with COVID-19.

Purpose of the Study:

  • To report the 3- and 6-month follow-up of patients with acute arterial thrombotic events secondary to COVID-19 infection.
  • To evaluate outcomes, including mortality, patency rates, and limb salvage, in this patient cohort.

Main Methods:

  • Prospective data collection of vascular surgery consultations for patients with COVID-19 presenting with arterial thrombotic events.
  • Analysis of treatment strategies including open surgical intervention, endovascular intervention, and anticoagulation.
  • Assessment of 3- and 6-month follow-up data for mortality, primary patency, and limb salvage rates.

Main Results:

  • Twenty-seven patients experienced acute arterial thrombotic events.
  • At 6 months, 48.0% of patients were deceased, with a cumulative primary patency rate of 61.9%.
  • The limb-salvage rate at 6 months was 89.2%.

Conclusions:

  • Patients with COVID-19 experiencing thrombotic events face high mortality and complication rates.
  • Intervention outcomes were characterized by relatively low patency rates.
  • Vigilant monitoring and management strategies are crucial for this high-risk patient group.
Abstract

Keywords:
AmputationCOVID-19Limb ischemiaPatencyThrombosis

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