Related Experiment Video
Updated: Oct 18, 2025

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
Published on: June 15, 2011
Syndrome du jour: The historiography and moral implications of Diagnosing Darwin
1University of Melbourne, Australia.
Abstract:
Diagnosing Darwin's health problems has a long history. Innumerable diagnoses have been proffered in letters, articles, and a handful of dedicated books. Diagnostic speculation has exhibited contrasting somatogenic or psychogenic preferences. Psychogenic accounts dominated mid-century but were soon challenged by somatic explanations citing specific infectious or toxic aetiologies. This tension remains, although psychogenic accounts have tended to be swamped by an array of somatogenic diagnoses championed by biomedical specialists. As a whole, this parade of diagnoses has a striking syndrome du jour quality. Successive conjectures speak of the preoccupations and diagnostic fads of their particular age. Moreover, for many participants in this diagnostic game, unconscious presentism combined with self-serving projection, turning the question of what ailed Darwin into something of a Rorschach test. Never far from the surface was a sometimes-fraught tussle over the man's reputation, animated by the moral valences of the conjectures in play. In a broader sense, this diagnostic game has shaped biographical accounts of Darwin and his career in some significant ways.
Related Concept Videos
Criticisms of the Evolutionary Perspective
Evolutionary psychology provides one explanation for these findings, suggesting...
Genomic Imprinting and Inheritance
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
The Ratio of X Chromosome to Autosomes
Normal male Drosophila has a ratio of one X chromosome to two sets of autosomes. In contrast, normal female...
Karyotyping
Animal Mitochondrial Genetics
Incomplete Dominance

