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Generation of a control human induced pluripotent stem cell line using the defective and persistent Sendai virus

Zhi Zhou1, Sho Yoshimatsu1, Emi Qian1

  • 1Department of Physiology, Keio University School of Medicine, Tokyo, Japan.

Stem Cell Research
|October 1, 2021
PubMed

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Stem cells are undifferentiated cells that divide and produce different cell types. Ordinarily, cells that have differentiated into a specific cell type are terminally differentiated; however, scientists have found a way to reprogram these mature cells so that they dedifferentiate and return to an unspecialized, proliferative state. These cells are pluripotent like embryonic stem cells—able to produce all cell types—and are called induced pluripotent stem cells (iPSCs).
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