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Management of Intracerebral Hemorrhage: Update and Future Therapies

Howard Kirshner1, Matthew Schrag2

  • 1Department of Neurology, Vanderbilt University School of Medicine, Nashville, TN, USA. howard.kirshner@vumc.org.

Current Neurology and Neuroscience Reports
|October 2, 2021
PubMed

Insights

Intracerebral hemorrhage (ICH) is a serious stroke type with high fatality. Current treatments focus on supportive care, but new medical and surgical advances offer hope for better patient outcomes.

Area of Science:

  • Neurology
  • Neurosurgery

Background:

  • Intracerebral hemorrhage (ICH) accounts for 15% of US strokes and 50% of fatal strokes.
  • Hypertension and cerebral amyloid angiopathy are primary causes of ICH.
  • Current ICH management includes edema control, blood pressure reduction, and coagulopathy correction.

Purpose of the Study:

  • To review new advances in the treatment of intracerebral hemorrhage.
  • To discuss emerging therapies that may improve ICH patient outcomes.

Main Methods:

  • Review of current standard of care for acute ICH.
  • Discussion of novel medical and surgical treatment approaches.

Main Results:

  • Supportive medical therapies in neurological intensive care units reduce mortality.
  • No definitive curative therapy currently exists for ICH, unlike mechanical thrombectomy for ischemic stroke.
  • Emerging surgical and medical strategies show promise for improved ICH management.

Conclusions:

  • While current ICH treatments focus on supportive care, significant advancements are on the horizon.
  • New therapeutic strategies, particularly in surgical management, are expected to enhance patient outcomes for intracerebral hemorrhage.
Abstract

Keywords:
Cerebral amyloid angiopathyCerebral hemorrhageExternal ventricular drainIntracerebral hemorrhageMicrohemorrhage

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