Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Sickle cell gnathopathy: radiologic assessment.

D L Brown, J I Sebes

Oral Surgery, Oral Medicine, and Oral Pathology

|June 1, 1986

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Heterogeneity of obstructive sleep apnea phenotypes after ischemic stroke: Outcome variation by cluster analysis.

Sleep medicine·2024

Same author

The prospective Hemophilia Inhibitor PUP Study reveals distinct antibody signatures prior to FVIII inhibitor development.

Blood advances·2020

Same author

Comparison of pneumococcal vaccination response in children with sickle cell disease: HbSS and HbSC.

Allergologia et immunopathologia·2019

Same author

Effective equations governing an active poroelastic medium.

Proceedings. Mathematical, physical, and engineering sciences·2017

Same author

Lymphocyte Subsets in the Adrenal Glands of Dogs With Primary Hypoadrenocorticism.

Veterinary pathology·2016

Same author

CHLOROPLAST DEVELOPMENT AND ULTRESTRUCTURE IN THE FRESHWATER RED ALGA BATRACHOSPERMUM(1).

Journal of phycology·2016

Same journal

The relation of the physical character of the diet to the health of the periodontal tissues; a critical review of the literature.

Oral surgery, oral medicine, and oral pathology·2010

Same journal

Psychosomatic factors in the etiology of periodontal disease; a critical review of the literature.

Oral surgery, oral medicine, and oral pathology·2010

Same journal

Bacteriologic investigations of the oral spirochetal flora in ulcerative stomatitis (Vincent's infection).

Oral surgery, oral medicine, and oral pathology·2010

Same journal

The nature and significance of infection in periodontal disease.

Oral surgery, oral medicine, and oral pathology·2010

Same journal

Histopathology of periodontal diseases.

Oral surgery, oral medicine, and oral pathology·2010

Same journal

Metastasis of chondromyxosarcoma to the jaw and tooth.

Oral surgery, oral medicine, and oral pathology·2010

See all related articles

Sickle cell gnathopathy, a dental issue in sickle cell anemia, can be accurately measured using the palate-alveolar ridge (PAR) angle. This radiographic method helps evaluate maxillary protrusion caused by marrow hyperplasia.

Area of Science:

Dentistry
Radiology
Genetics

Background:

Sickle cell anemia can cause skeletal abnormalities, including dental issues known as sickle cell gnathopathy.
Objective evaluation methods are needed to assess these changes.

Purpose of the Study:

To objectively evaluate sickle cell gnathopathy using lateral skull radiographs.
To compare hard palate length and palate-alveolar ridge (PAR) angle in patients with sickle cell anemia and controls.

Main Methods:

Lateral skull radiographs were taken from 50 sickle cell anemia patients and 25 controls.
Measurements included hard palate length, PAR angle, and Sella-Nasion-Anterior nasal spine (SNA) angle.
Statistical comparison was performed between the patient and control groups.

Related Experiment Videos

Main Results:

A significant difference was observed in the PAR angle between sickle cell anemia patients and controls.
No significant differences were found in hard palate length or SNA angle.
Maxillary protrusion in sickle cell gnathopathy is primarily associated with an increased PAR angle.

Conclusions:

The PAR angle is a simple and accurate radiographic measurement for evaluating sickle cell gnathopathy.
Marrow hyperplasia is the likely cause of maxillary overgrowth in sickle cell anemia.
Radiographic assessment of the PAR angle aids in understanding and managing sickle cell gnathopathy.