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Updated: Oct 18, 2025

Measurement of Heme Synthesis Levels in Mammalian Cells
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Hemoglobin allostery and pharmacology

Andrea Bellelli1, Jeremy R H Tame2

  • 1Department of Biochemical Sciences "A. Rossi Fanelli", Sapienza University of Rome, Rome, Italy.

Molecular Aspects of Medicine
|October 3, 2021
PubMed
Summary

Hemoglobin (Hb) oxygen affinity can be pharmacologically modulated to treat blood disorders like sickle cell anemia and enhance cancer radiotherapy. This review explores Hb pharmacology and its therapeutic applications.

Keywords:
HemoglobinOxygen affinityOxygen transportTissue oxygenation

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