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Updated: Oct 18, 2025

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
Published on: July 5, 2022
The epidemiology, pathophysiological mechanisms, and management toward COVID-19 patients with Type 2 diabetes: A
Yun Yin1, Kristen E Rohli2, Pengyue Shen3
1International Institute of Spatial Lifecourse Epidemiology (ISLE), Wuhan University, Wuhan, China; West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.
Abstract:
This review comprehensively summarizes epidemiologic evidence of COVID-19 in patients with Type 2 diabetes, explores pathophysiological mechanisms, and integrates recommendations and guidelines for patient management. We found that diabetes was a risk factor for diagnosed infection and poor prognosis of COVID-19. Patients with diabetes may be more susceptible to adverse outcomes associated with SARS-CoV-2 infection due to impaired immune function and possible upregulation of enzymes that mediate viral invasion. The chronic inflammation caused by diabetes, coupled with the acute inflammatory reaction caused by SARS-CoV-2, results in a propensity for inflammatory storm. Patients with diabetes should be aware of their increased risk for COVID-19.
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