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Covid-19 associated Mucormycosis: A case report
Oshan Shrestha1, Reetu Sharma Baral1
1Nobel Medical College and Teaching Hospital, Kathmandu University, Biratnagar, Nepal.
Journal of Nepal Health Research Council
|October 3, 2021
Summary
Coronavirus disease 2019 (COVID-19) can lead to severe complications like acute respiratory distress syndrome. This study highlights a rise in aggressive fungal infections, specifically rhino-orbital mucormycosis, in COVID-19 patients with uncontrolled diabetes.
Area of Science:
- Infectious Diseases
- Ophthalmology
- Critical Care Medicine
Background:
- Coronavirus disease 2019 (COVID-19) is frequently associated with acute respiratory distress syndrome, necessitating intensive supportive care.
- Mucormycosis, an uncommon fungal infection, has seen an increase during the COVID-19 pandemic, particularly in patients with comorbidities.
Observation:
- A case of rhino-orbital mucormycosis is presented in a patient with uncontrolled hyperglycemia.
- The infection presented aggressively, affecting the ethmoidal sinus and frontal recess.
Findings:
- Histopathological examination confirmed invasive necro-inflammatory infection.
- Numerous Mucormycosis hyphae were identified in the affected tissues.
Implications:
- This case underscores the critical need for vigilance regarding opportunistic fungal infections in immunocompromised COVID-19 patients.
- Early diagnosis and management of mucormycosis are crucial for improving outcomes in this vulnerable population.

