Related Experiment Video
Updated: Oct 18, 2025

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
Published on: March 6, 2019
Myositis ossificans: a rare neonatal presentation.
Chelsea B Dennison1, Ivey R Royall2, Kimberly M Beavers2
1Department of Diagnostic Radiology, AdventHealth Orlando, 601 E. Rollins St., Orlando, FL, 32803, USA. chelsea.dennison.md@adventhealth.com.
Myositis ossificans, a soft-tissue pseudotumor, is rare in infants. This study details an unusual case in the perinatal period, highlighting key imaging findings for early diagnosis.
Area of Science:
- Orthopedics
- Radiology
- Pediatric Pathology
Background:
- Myositis ossificans is a benign, ossifying soft-tissue pseudotumor.
- Typically affects men aged 30-40 years post-trauma.
- Extremely rare in children under 10 years old.
Observation:
- This report presents an exceptionally unusual case of myositis ossificans.
- The condition manifested in the immediate perinatal period, shortly after birth.
- Key imaging findings that aid in differentiation are reviewed.
Findings:
- Myositis ossificans presents unique imaging characteristics distinct from malignant soft-tissue tumors.
- Early and accurate differentiation is crucial for patient management.
- This case underscores the possibility of congenital or perinatal onset.
Implications:
- Accurate diagnosis of myositis ossificans prevents unnecessary and potentially harmful procedures.
- Recognizing rare presentations like this improves diagnostic capabilities in neonates.
- Understanding the imaging spectrum is vital for pediatric radiologists and orthopedic surgeons.
Related Concept Videos
Disorders of the Skeletal Muscle
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
Bone Formation by Intramembranous Ossification
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into ...
Formation of Muscle Fibers from Myoblasts
Muscle progenitor cells (MPCs) are formed from the myotomes. MPCs express genes that encode the transcription factors Pax3 and Pax7. Along with Pax 3/7, other transcription...
Myocarditis II: Clinical Features and Diagnostic Tests
Myocarditis I: Introduction
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...

