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Updated: Oct 18, 2025
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Detection of amyotrophic lateral sclerosis disease from event-related potentials using variational mode decomposition
Fırat Orhanbulucu1,2, Fatma Latifoğlu2
1Department of Biomedical Engineering, Inonu University, Malatya, Turkey.
Abstract:
This study, it was aimed to contribute to the literature on Amyotrophic lateral sclerosis (ALS) diagnosis and Brain-Computer Interface (BCI) technologies by analyzing the electroencephalography (EEG) signals obtained as a result of visual stimuli and attention from ALS patients and healthy controls. It was observed that the success rate significantly increased both in the occipital and central regions in all classifiers, especially in the entropy features. The most successful classification was obtained with the Naïve Bayes (NB) classifier using the Morphological Features (MF) + Variational Mode Decomposition (VMD) -Entropy features at 88.89% in the occipital region and 94.44% in the central region.
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