The prevalence of human papillomavirus in paediatric tonsils in Southwestern Ontario
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Published on: June 14, 2020
M Wojtera1, J W Barrett1,2, J E Strychowsky1,2
1Schulich School of Medicine and Dentistry, London, Ontario, Canada.
Objective:
To determine the prevalence of human papillomavirus in paediatric tonsils in Southwestern Ontario, Canada.
Materials And Methods:
Patients aged 0-18 years undergoing tonsillectomy were recruited. Two specimens (left and right tonsils) were collected from each participant. Tonsillar DNA was analysed using quantitative polymerase chain reaction to determine the presence of human papillomavirus subtypes 6, 11, 16 or 18.
Results:
A total of 102 patients, aged 1-18 years (mean age of 5.7 years), were recruited. Ninety-nine surveys were returned. There were 44 females (44.4 per cent) and 55 males (55.6 per cent). Forty patients (40.4 per cent) were firstborn children and 73 (73.7 per cent) were delivered vaginally. Six mothers (6.1 per cent) and one father (1.0 per cent) had prior known human papillomavirus infection, and one mother (1.0 per cent) had a history of cervical cancer. All tonsil specimens were negative for human papillomavirus subtypes 6, 11, 16 and 18.
Conclusion:
No human papillomavirus subtypes 6, 11, 16 or 18 were found in paediatric tonsil specimens from Southwestern Ontario.
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