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Right Heart Morphology and Its Association With Excessive and Deficient Cardiac Visceral Adipose Tissue

Domagoj Vučić1, Nikola Bijelić2, Edi Rođak2

  • 1Department for Internal Medicine, Division of Cardiology, General Hospital Doctor Josip Benčević, Slavonski Brod, Croatia.

Clinical Medicine Insights. Cardiology
|October 4, 2021
PubMed

Insights

Visceral adipose tissue impacts heart health, influencing conditions like coronary disease and hypertension. This study explores its specific effects on right heart morphology, offering new insights into cardiovascular pathogenesis.

Area of Science:

  • Cardiovascular Science
  • Metabolic Disease Research
  • Adipose Tissue Biology

Background:

  • Visceral adipose tissue is a key risk factor for cardiovascular diseases, hypertension, diabetes, and metabolic syndrome.
  • Cardiac adipose tissue plays roles in thermogenesis, mechanical protection, energy storage, and acts as an endocrine organ secreting cytokines.
  • Limited knowledge exists on how visceral adipose tissue, in excess or deficiency, affects cardiac morphology, particularly the right heart.

Purpose of the Study:

  • To investigate the influence of visceral adipose tissue on cardiac morphology.
  • To specifically examine the impact of visceral adipose tissue excess or deficiency on right heart morphology.

Main Methods:

  • Non-invasive imaging methods are used to quantify cardiac adipose tissue.
  • Analysis of existing literature and data on visceral adipose tissue and cardiac morphology.

Main Results:

  • Visceral adipose tissue is implicated in the pathogenesis of major cardiovascular and metabolic diseases.
  • Cardiac adipose tissue functions include thermogenesis, mechanical support, energy storage, and endocrine signaling via cytokines.
  • Deficiency in cardiac adipose tissue correlates with increased mortality and morbidity in chronic conditions.

Conclusions:

  • Visceral adipose tissue significantly influences cardiovascular health and disease development.
  • Further research is needed to fully elucidate the specific effects of visceral adipose tissue on right heart morphology.

Keywords:
Cachexiaepicardial adipose tissuehistologyimagingright heart morphology

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