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Related Concept Videos

Visual Agnosia01:12

Visual Agnosia

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Visual agnosia is a condition characterized by the inability to recognize visually presented objects despite having normal vision. For instance, a person with visual agnosia can describe the shape and color of an object but cannot identify or name it. This impairment does not affect their visual field, acuity, color vision, brightness discrimination, language, or memory. An example of this condition in a social setting is someone at a dinner party asking for "that silver thing with a round...
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Updated: Oct 18, 2025

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients
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Diagnostic Evaluation of Visual Snow.

Michael S Vaphiades1, Brendan Grondines1, Kasey Cooper1

  • 1Department of Ophthalmology, University of Alabama, Birmingham, AL, United States.

Frontiers in Neurology
|October 4, 2021
PubMed
Summary
This summary is machine-generated.

Patients with visual snow (VS) and VS syndrome (VSS) often have normal results on standard eye exams and visual field tests. Further testing like imaging or electrophysiology is only needed if initial evaluations are abnormal.

Keywords:
CTMRIOCTelecroretinographyvisual snowvisual snow syndrome

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Area of Science:

  • Ophthalmology
  • Neuro-ophthalmology
  • Medical Diagnostics

Background:

  • Visual snow (VS) is a rare neurological condition characterized by continuous, low-level visual noise.
  • Visual snow syndrome (VSS) encompasses VS with additional associated symptoms, requiring careful diagnostic evaluation.
  • Determining the appropriate diagnostic pathway for VS and VSS is crucial for effective patient management.

Purpose of the Study:

  • To identify criteria for standard ophthalmologic testing versus advanced investigations in patients with VS and VSS.
  • To differentiate patients who require basic visual field testing from those needing macular SD-OCT, electrophysiology, or neuroimaging.

Main Methods:

  • Retrospective review of 52 patients diagnosed with VS and VSS across three institutions (2015-2021).
  • Data collection included patient history, ophthalmic examination findings, and results from visual field tests, SD-OCT, electrophysiology (VEP, ffERG, mfERG), and neuroimaging (MRI).

Main Results:

  • Out of 52 patients, 8 met VSS criteria. Mean age was 25 years (range 7-79).
  • Most patients (92%) had normal color vision, and 88% had normal funduscopic exams.
  • Standard tests like Humphrey visual fields (86% normal) and VEPs (95% normal) were frequently normal; advanced testing (SD-OCT, ffERG, mfERG) was also largely normal, with only 4 patients showing abnormal electrophysiology. MRI was normal in 78% of cases, with one case of optic neuritis.

Conclusions:

  • For typical presentations of VS and VSS with normal initial testing, a thorough history, neuro-ophthalmologic exam, and automated perimetry suffice.
  • Abnormal findings during initial evaluations warrant further ancillary testing, including electrophysiology and neuroimaging, to investigate potential underlying pathologies.