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Bordetella pertussis: An agent not to be forgotten in Qatar
Samina Hasnain1, Jesha Mundodan1, Soha Al Bayat1
1EPI Section, Health Promotion and Communicable Disease Control, Ministry of Public Health, Doha, Qatar jmundodan@moph.gov.qa.
Insights
Five infants in Qatar were diagnosed with pertussis in 2019, highlighting the potential re-emergence of this vaccine-preventable disease. Maintaining high vaccination coverage and antenatal Tdap immunization is crucial for prevention.
Area of Science:
- Epidemiology
- Immunology
- Public Health
Background:
- Pertussis (whooping cough) is a highly contagious respiratory infection caused by *Bordetella pertussis*.
- Infants are most vulnerable to severe pertussis complications, especially before completing their primary vaccination series.
- Qatar maintained high pertussis vaccine coverage (>95%) with no indigenous cases reported between 2010-2018, though imported cases occurred in 2016.
Observation:
- All five confirmed pertussis cases in 2019 were infants under one year old.
- Three of the five infants had not received any pertussis-containing vaccine doses.
- Mothers of the confirmed cases had not received antenatal tetanus, diphtheria, and acellular pertussis (Tdap) vaccination during pregnancy.
Findings:
- The study describes five confirmed infant pertussis cases in Qatar during 2019.
- Vaccination status varied, with some infants under-immunized or unvaccinated.
- A lack of maternal Tdap vaccination was noted in all confirmed cases.
Implications:
- Pertussis re-emergence is a potential concern in Qatar.
- Maintaining high vaccine coverage and active immunization are key preventive strategies.
- Increased awareness of antenatal Tdap vaccination importance is necessary to protect infants.
Background:
Pertussis (whooping cough) is a vaccine-preventable disease caused by the bacterium Bordetella pertussis that is spread by airborne respiratory droplets. Clinical symptoms vary from infants to adults and are most contagious before the onset of symptoms. Infants are at the highest risk of infection, especially before they are old enough to receive at least two doses of pertussis-containing vaccine. There have been no indigenous cases of pertussis in Qatar since 2010 until 2018, due to free pertussis-containing vaccines under the National Immunization Schedule of Qatar, with coverage consistently above 95%. Two cases were reported in 2016 but were found to be imported. In 2019, 20 infants were reported as suspected pertussis to the Health Promotion and Communicable Disease Control (HP-CDC), Ministry of Public Health (MOPH), Qatar; of them, five were laboratory confirmed as pertussis.
Objective:
This study aimed to describe the five confirmed cases of pertussis reported to HP-CDC, MOPH, Qatar, between January 1 and December 30, 2019. Summary of Cases: All five confirmed pertussis cases were under one year old, and three were boys. All except one were immunized-for-age, and three had not received any doses of pertussis-containing vaccine and in none of the cases had the mother received tetanus, diphtheria, and acellular pertussis (Tdap) vaccine during pregnancy. All infants were born in Qatar, and two were Qatari nationals.
Conclusion:
There may be a possibility of re-emergence of pertussis in Qatar. Active immunization and coverage maintenance are the best tools to prevent re-emergence. Undiagnosed and untreated pertussis cases are potential sources of infection. The partial or unimmunized groups may be significantly at risk, especially during infancy and before reaching the age to complete the three primary doses of diphtheria, tetanus, and pertussis vaccines. Focus on increasing awareness among those providing antenatal care, regarding the importance of Tdap vaccination during pregnancy, is necessary.
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