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Updated: Oct 18, 2025

Measuring the Functional Abilities of Children Aged 3-6 Years Old with Observational Methods and Computer Tools
Published on: June 20, 2020
Hybrid type 1 effectiveness/implementation trial of the international Guide for Monitoring Child Development:
Abhishek Raut1, Revan Mustafayev2, Roopa Srinivasan3
1Department of Community Medicine, Dr. Sushila Nayar School of Public Health, Mahatma Gandhi Institute of Medical Sciences, Sevagram, Maharashtra, India.
Insights
The Guide for Monitoring Child Development (GMCD) intervention improves early childhood development in low-income countries. This study evaluates its effectiveness and implementation in India and Guatemala.
Area of Science:
- Global child development
- Early childhood intervention programs
- Implementation science
Background:
- Over 40% of young children in low- and middle-income countries risk developmental delays.
- The Guide for Monitoring Child Development (GMCD) is an early intervention package designed to address these challenges.
- Individualized intervention plans are crucial for supporting young children and their families.
Purpose of the Study:
- To conduct a hybrid type 1 effectiveness-implementation evaluation of the GMCD intervention.
- To assess the impact of GMCD on developmental functioning and nurturing care in young children.
- To explore factors influencing the effectiveness of GMCD implementation in diverse settings.
Main Methods:
- A cluster-randomised trial involving 624 children aged 0-24 months in India and Guatemala.
- Intervention delivered via a digital mobile device interface by frontline workers over 12 months.
- Outcomes assessed using the Bayley Scales of Infant Development and Home Observation for Measurement of the Environment Scale; implementation evaluated using the RE-AIM framework.
Main Results:
- Effectiveness of the GMCD intervention on child development and nurturing care will be assessed.
- Implementation effectiveness will be measured using the Reach, Effectiveness, Adoption, Implementation, Maintenance (RE-AIM) framework.
- Qualitative analysis will identify determinants of high versus low implementation effectiveness.
Conclusions:
- The GMCD intervention has the potential to address critical developmental needs in young children.
- This study will provide valuable insights into the effectiveness and implementability of GMCD in resource-limited settings.
- Findings will inform the scale-up of effective early childhood interventions globally.
Introduction:
More than 40% of children under 5 years of age in low-income and middle-income countries are at risk of not reaching their developmental potential. The international Guide for Monitoring Child Development (GMCD) early intervention package is a comprehensive programme to address developmental difficulties using an individualised intervention plan for young children and their families. We will conduct a hybrid type 1 effectiveness-implementation evaluation of the GMCD intervention in rural India and Guatemala.
Methods And Analysis:
Using a cluster-randomised design, 624 children aged 0-24 months in 52 clusters (26 in India, 26 in Guatemala) will be assigned to usual care or the GMCD intervention plus usual care delivered by frontline workers for 12 months. After 12 months, the usual care arm will cross over to the intervention, which will continue for 12 additional months (24 total). The intervention will be delivered using a digital mobile device interface. Effectiveness will be assessed for developmental functioning (Bayley Scales of Infant Development, 3rd edition) and nurturing care (Home Observation for Measurement of the Environment Scale) outcomes. Implementation will be assessed using the Reach, Effectiveness, Adoption, Implementation, Maintenance framework. Explanatory qualitative analysis guided by the Consolidated Framework for Implementation Research will explore determinants between clusters with high versus low implementation effectiveness.
Ethics And Dissemination:
The study has been approved by the Institutional Review Boards of Brigham and Women's Hospital, Mahatma Gandhi Institute of Medical Sciences and Maya Health Alliance; and by the Indian Council of Medical Research/Health Ministry Screening Committee. Key study findings will be published in international open-access journals.
Trial Registration Number:
NCT04665297, CTRI/2020/12/029748.
Protocol Version:
1.0 (12 November 2020).
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