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Updated: Oct 18, 2025

The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy rNAION
Published on: November 20, 2016
Chronic recurrent multifocal osteomyelitis, central retinal artery occlusion and optic neuropathy: A new association
Michael S Vaphiades1,2, Kevin E Lai3,4,5, Lanning B Kline1
1Departments of Ophthalmology, University of Alabama, Birmingham, AL, USA.
Purpose:
To report a patient with chronic recurrent multifocal osteomyelitis (CRMO) complicated by optic neuropathy and central retinal artery occlusion (CRAO).
Observations:
CRMO is a noninfectious, inflammatory bone disorder. It is thought to be an autoimmune condition related to an imbalance of pro- and anti-inflammatory cytokines. Retinal vasculitis has been reported in a patient with CRMO but not CRAO or optic neuropathy.
Conclusions:
We expanded the list of ophthalmic involvement of CRMO to include CRAO and optic neuropathy.
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