Infectious complications after transrectal prostate biopsy is increased in patients with chronic idiopathic
Cahit Şahin1, Eyüp Veli Küçük2, Ahmet Tahra2
1Department of Urology. Health Sciences University. Kartal Dr. Lütfi Kırdar Training & Research Hospital. Istanbul. Turkey.
Objective:
This study aims to compare infectious complications after a prostate biopsy in patients with or without chronic idiopathic constipation (CIC).
Methods:
Six hundred and sixty-three patients who underwent a transrectal ultrasound-guided biopsy (TRUSBx) of the prostate between 2012 and 2018 were evaluated prospectively. Patients were divided into two groups according to their CIC status and monitored for complications. CIC was defined by the Rome III criteria. Multivariate analysis was performed to assess the risk factors.
Results:
Thirty-five patients (5.8%) developed a urinary tract infection (UTI) while sepsis occurred in only three cases (0.5%). CIC was found as a risk factor for infection. Infection occurred in 18.1% of the men with CIC compared to 2.3% of those without CIC (p=0.001). Sepsis occurred in 1.4% of the men with CIC compared to vs 0.2% of those without CIC (p=0.68). In multivariate analysis, CIC (OR of 9.27 and 95% CI 4.40-19.54, p<0.05) and Diabetes Mellitus (OR of 3.11 and 95% CI 1.52-6.36, p=0.002) were associated with an increased risk factor of UTI and sepsis.
Conclusions:
We demonstrated that CIC is an important risk factor of infection after a prostate biopsy. Prevention is important to minimize complications after this very common worldwide procedure.
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