Related Experiment Video
Updated: Oct 18, 2025
09:28
One-step Metabolomics: Carbohydrates, Organic and Amino Acids Quantified in a Single Procedure
Published on: June 25, 2010
13.3K
Continuous Ketone Monitoring Consensus Report 2021
Kevin T Nguyen1, Nicole Y Xu1, Jennifer Y Zhang1
1Diabetes Technology Society, Burlingame, CA, USA.
Journal of Diabetes Science and Technology
|October 4, 2021
Summary
Continuous ketone monitoring (CKM) technology shows promise for preventing diabetic ketoacidosis (DKA). Experts developed 30 consensus conclusions to guide the safe and effective development and application of CKM devices for people with diabetes.
Area of Science:
- Diabetes Technology
- Biomedical Engineering
- Clinical Chemistry
Background:
- Diabetic ketoacidosis (DKA) is a serious complication of diabetes.
- Current methods for ketone monitoring have limitations.
- Continuous ketone monitoring (CKM) offers a potential solution for improved DKA prevention.
Purpose of the Study:
- To review the medical literature on ketone production, measurement, and monitoring.
- To assess the performance and potential of continuous ketone monitors (CKMs).
- To develop consensus conclusions on the development and application of CKM technology.
Main Methods:
- A panel of 20 US-based experts in diabetes technology convened virtually.
- Literature review across ten key topics related to ketone monitoring and DKA.
- Development and unanimous adoption of 30 consensus conclusions regarding CKMs.
Main Results:
- The panel summarized existing medical literature on ketone physiology and measurement.
- The performance of the first reported continuous ketone monitor in human trials was reviewed.
- Potential integration of CKMs with insulin delivery systems for DKA prevention was discussed.
Conclusions:
- CKM technology has the potential to significantly benefit individuals with diabetes.
- 30 consensus conclusions were established to guide the development of safe and effective CKMs.
- The findings aim to support the advancement of CKM technology for DKA prevention and management.
Related Concept Videos
01:24Diagnosing Acidosis and Alkalosis
657
Diagnosing acid-base imbalances involves systematically analyzing arterial blood samples, focusing on three key measurements: pH, bicarbonate (HCO3−) concentration, and carbon dioxide partial pressure (PCO2). This analysis follows a four-step process that helps identify the imbalance's underlying cause and nature.
First, the pH level is assessed to determine whether the blood pH is normal (7.35–7.45), low (acidosis), or high (alkalosis).
Next, the PCO2 and...
First, the pH level is assessed to determine whether the blood pH is normal (7.35–7.45), low (acidosis), or high (alkalosis).
Next, the PCO2 and...
657
01:19Special considerations while measuring oxygen saturation
732
Assessing respiratory rate concurrently with pulse measurement is fundamental to patient care, providing valuable insights into the patient's respiratory function. The normal breathing rate for an adult usually falls within a normal range of 12 to 20 breaths per minute. Abnormal respiratory rates can signal underlying health conditions or the need for immediate intervention.
Ensuring accuracy in vital sign recordings while prioritizing patient comfort and minimizing anxiety is...
Ensuring accuracy in vital sign recordings while prioritizing patient comfort and minimizing anxiety is...
732
01:30Pulse rhythm
998
Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac...
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac...
998
01:23Holter Monitor: 24-Hour Monitoring
483
Holter monitoring is a continuous electrocardiography (ECG) recording that tracks the heart's electrical activity over an extended period, generally 24 to 48 hours. This noninvasive diagnostic tool detects irregular heart rhythms that may not be captured during a standard ECG performed in a clinical setting.DeviceThe Holter monitor is a portable, small device connected to several electrodes on the patient's chest. These electrodes detect the heart's electrical signals and transmit them to the...
483
01:30Continuous Renal Replacement Therapy
193
Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
193
01:29Chronic Pancreatitis II: Collaborative Care
142
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
Assessment:
142